Appearance
🎉 your library🥳
"Croydon Road Recreation Ground is a public park located in Beckenham in the London Borough of Bromley. It is near the High St and adjacent to Beckenham Beacon. The park features a café and bandstand, as well as a bowling green and other sports facilities. The park was laid out by the Sydenham firm Reid and Bornemann in 1890 and was formally opened on 23 September 1891. Airmail Balloon Flight plaque The UK's first manned airmail flight left from here in 1902, travelling to Calais by hot air balloon The event was held to celebrate the coronation of King Edward VII. The crew were A E Gaudron, a French balloonist and Dr. Barton, a local medical practitioner. Mail was dropped at three points in Kent before the balloon itself then crossed the Channel before landing near Calais. On 16 August 1969, David Bowie helped organise and played at the Growth Summer Festival a one-day festival that played from the bandstand in the park. Now known as the Bowie Bandstand, it was built by the McCallum and Hope Iron Foundry of Glasgow and erected in 1905. It was listed Grade II on the National Heritage List for England in 2019 as a "rare and substantial example of cast-iron work" by the McCallum and Hope Iron Foundry, and for its association with Bowie. On 15 September 2013, the park hosted a "Memory of a Free Festival" event, commemorating the 1969 festival. References Category:Parks and open spaces in the London Borough of Bromley Category:1891 establishments in England Category:1891 in London "
""
"Psilocin (also known as 4-HO-DMT, 4-hydroxy DMT, psilocine, psilocyn, or psilotsin) is a substituted tryptamine alkaloid and a serotonergic psychedelic substance. It is present in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin. Psilocin is a Schedule I drug under the Convention on Psychotropic Substances. The mind-altering effects of psilocin are highly variable, subjective and resemble those of LSD and DMT. Chemistry Psilocin and its phosphorylated cousin, psilocybin, were first isolated and named in 1958 by Swiss chemist Albert Hofmann. Hofmann obtained the chemicals from laboratory-grown specimens of the entheogenic mushroom Psilocybe mexicana. Hofmann also succeeded in finding the synthetic routes to these chemicals. Psilocin can be obtained by dephosphorylation of natural psilocybin under strongly acidic or under alkaline conditions (hydrolysis). Another synthetic route uses the Speeter-Anthony tryptamine synthesis starting from 4-hydroxyindole. Psilocin is relatively unstable in solution due to its phenolic hydroxy (-OH) group. In the presence of oxygen it readily forms bluish and dark black degradation products. Similar products are also formed under acidic conditions in the presence of oxygen and Fe3+ ions (Keller's reagent). = Structural analogs = Sulfur analogs are known with a benzothienyl replacement as well as 4-SH-DMT.A Hofmann, F Troxler, Swiss 421,960 (1967); CA 68:95680n 1-Methylpsilocin is a functionally 5-HT2C receptor preferring agonist. 4-Fluoro-N,N-dimethyltryptamine is known. O-Acetylpsilocin (4-AcO-DMT) is an acetylated analog of psilocin. Additionally, replacement of a methyl group at the dimethylated nitrogen with an isopropyl or ethyl group yields 4-HO-MIPT (4-hydroxy-N-methyl-N- isopropyltryptamine) and 4-HO-MET (4-hydroxy-N-methyl-N-ethyltryptamine), respectively. Pharmacology Psilocin is the pharmacologically active agent in the body after ingestion of psilocybin or some species of psychedelic mushrooms. Psilocybin is rapidly dephosphorylated in the body to psilocin which acts as a 5-HT2A, 5-HT2C and 5-HT1A agonist or partial agonist. Psilocin exhibits functional selectivity in that it activates phospholipase A2 instead of activating phospholipase C as the endogenous ligand serotonin does. Psilocin is structurally similar to serotonin (5-HT), differing only by the hydroxyl group being on the 4-position rather than the 5 and the dimethyl groups on the nitrogen. Its effects are thought to come from its agonist activity at 5-HT2A serotonin receptors in the prefrontal cortex. Psilocin has no significant effect on dopamine receptors (unlike LSD) and only affects the noradrenergic system at very high dosages. Psilocin's half-life ranges from 1 to 3 hours. : See psilocybin for more details Behavioral and non-behavioral effects Dried psilocybin mushrooms. (Notice the characteristic blue bruising by the stems of the mushrooms.) Its physiological effects are similar to a sympathetic arousal state. Specific effects observed after ingestion can include but are not limited to tachycardia, dilated pupils, restlessness or arousal, euphoria, open and closed eye visuals (common at medium to high doses), synesthesia (e.g. hearing colours and seeing sounds), increased body temperature, headache, sweating and chills, and nausea. Psilocin acts as a 5-HT2A, 5-HT2C and 5-HT1A agonist or partial agonist. Receptors are claimed to significantly regulate visuals, decision making, mood, decreased blood pressure and heart rate. There is virtually no direct lethality associated with psilocin. There is virtually no withdrawal syndrome when chronic use of this drug is ceased. There is cross tolerance among psilocin, mescaline, LSD, and other 5-HT2A, 5-HT2C, and 5-HT1A agonists due to down-regulation of these receptors. Legal status The United Nations Convention on Psychotropic Substances (adopted in 1971) requires its members to prohibit psilocybin, and parties to the treaty are required to restrict use of the drug to medical and scientific research under strictly controlled conditions. =Australia= Psilocin is considered a Schedule 9 prohibited substance in Australia under the Poisons Standard (October 2015).Poisons Standard October 2015 https://www.comlaw.gov.au/Details/F2015L01534 A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities. =Russia= Psilocin and psilocybin are banned in Russia as narcotic drugs with a criminal penalty for possession of at least 50 mg. See also References External links * 4-HO-DMT entry in TiHKAL Category:Psychedelic drugs Category:Psychedelic tryptamines Category:Entheogens Category:Mycotoxins Category:Tryptamine alkaloids Category:Hydroxyarenes Category:Serotonin receptor agonists "